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Human Relaxin-2
更新時間：2013-06-19
點擊次數：2027
| Synonyms : | H2 relaxin, RLN2 | |||||||||||||||||||
| Description : | Relaxin-2 is a peptide hormone structurally related to insulin, which is expressed in the placenta, decidua, prostate, and in the ovary during pregnancy. Of the three known relaxin genes, Relaxin-2 is the only relaxin known to circulate in the blood. Relaxin-2 binds specifically to the LGR7 and LGR8 receptors, previously identified as an “orphan” G protein coupled receptors. Signaling by Relaxin-2 through its target receptors enhances the growth of pubic ligaments and ripening of the cervix during birth. Recombinant Relaxin-2 is a nonglycosylated 6.0 kDa disulfide linked heterodimeric protein consisting of a 24 amino acid A-chain and a 29 amino acid B-chain. | |||||||||||||||||||
| Catalog #: | 130-15 | |||||||||||||||||||
| Source : | E.coli | |||||||||||||||||||
| Stability : | The lyophilized protein is stable for at least 2 years from date of receipt at -200C. Reconstituted Relaxin-2 is stable for at least 3 months when stored in working aliquots with a carrier protein at -200C. Avoid repeated freeze/thaw cycles. | |||||||||||||||||||
| Purity : | Greater than 98% by SDS-PAGE gel and HPLC analyses. | |||||||||||||||||||
| Endotoxin Level : | Endotoxin level is less than 0.1 ng per μg （1EU/μg）. | |||||||||||||||||||
| Biological Activity : | Data Not Available | |||||||||||||||||||
| AA Sequence : | A-Chain: QLYSALANKC CHVGCTKRSL ARFC B-Chain: DSWMEEVIKL CGRELVRAQI AICGMSTWS | |||||||||||||||||||
| PubMed Link : | Relaxin-2 | |||||||||||||||||||
| Country of Origin : | USA | |||||||||||||||||||
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